Theme: Hereditary Cancer Diseases V.
Reviews
Klin Onkol 2019; 32(Suppl 2): 6-13.
DOI: 10.14735/amko2019S6.
Keywords: genes – BRCA1 – BRCA2 – genetic testing – prophylactic mastectomy – salpingo-oophorectomy – high-throughput nucleotide sequencing
Authors: Foretová Lenka, Navrátilová Marie, Svoboda Marek, Vašíčková Petra, Sťahlová Hrabincová Eva, Házová Jana, Kleiblová Petra, Kleibl Zdeněk, Macháčková Eva, Palácová Markéta, Petráková Katarína2019-08-18:Recommendations for Preventive Care for Women with Rare Genetic Cause of Breast and Ovarian Cancer
Keywords: genes – BRCA1 – BRCA2 – genetic testing – prophylactic mastectomy – salpingo-oophorectomy – high-throughput nucleotide sequencing
Authors: Foretová Lenka, Navrátilová Marie, Svoboda Marek, Vašíčková Petra, Sťahlová Hrabincová Eva, Házová Jana, Kleiblová Petra, Kleibl Zdeněk, Macháčková Eva, Palácová Markéta, Petráková Katarína2019-08-18:Recommendations for Preventive Care for Women with Rare Genetic Cause of Breast and Ovarian Cancer
Klin Onkol 2019; 32(Suppl 2): 14-23.
DOI: 10.14735/amko2019S14.
Keywords: hereditary cancer syndromes – autozomal recessive inheritance – heterozygote – mutation – risk of cancer – predictive testing
Authors: Koudová Monika, Puchmajerová Alena2019-08-18:Risks of Solid Tumors in Heterozygous Carriers of Recessive Syndromes
Keywords: hereditary cancer syndromes – autozomal recessive inheritance – heterozygote – mutation – risk of cancer – predictive testing
Authors: Koudová Monika, Puchmajerová Alena2019-08-18:Risks of Solid Tumors in Heterozygous Carriers of Recessive Syndromes
Klin Onkol 2019; 32(Suppl 2): 24-30.
DOI: 10.14735/amko2019S24.
Keywords: breast cancer – BRCA1/2 mutation – genomic tests – platinum salts – PARP inhibitors
Authors: Palácová Markéta2019-08-18:Breast Cancer in BRCA1/2 Mutation Carriers – Do We Treat It Differently? Focus on Systemic Therapy for BRCA1/2 Associated Breast Cancer
Keywords: breast cancer – BRCA1/2 mutation – genomic tests – platinum salts – PARP inhibitors
Authors: Palácová Markéta2019-08-18:Breast Cancer in BRCA1/2 Mutation Carriers – Do We Treat It Differently? Focus on Systemic Therapy for BRCA1/2 Associated Breast Cancer
Klin Onkol 2019; 32(Suppl 2): 79-91.
DOI: 10.14735/amko2019S79.
Keywords: ovarian neoplasms – child – adolescent – hereditary cancer syndromes
Authors: Plevová Pavlína, Geržová Hedvika2019-08-18:Genetic Causes of Rare Pediatric Ovarian Tumors
Keywords: ovarian neoplasms – child – adolescent – hereditary cancer syndromes
Authors: Plevová Pavlína, Geržová Hedvika2019-08-18:Genetic Causes of Rare Pediatric Ovarian Tumors
Klin Onkol 2019; 32(Suppl 2): 92-96.
DOI: 10.14735/amko2019S92.
Keywords: colorectal carcinoma – Lynch syndrome – gastrointestinal polyposes
Authors: Pokorová Šárka, Fabián Pavel2019-08-18:Gastrointestinal Polyposes and Lynch Syndrome – a Pathologist’s Perspective
Keywords: colorectal carcinoma – Lynch syndrome – gastrointestinal polyposes
Authors: Pokorová Šárka, Fabián Pavel2019-08-18:Gastrointestinal Polyposes and Lynch Syndrome – a Pathologist’s Perspective
Klin Onkol 2019; 32(Suppl 2): 97-108.
DOI: 10.14735/amko2019S97.
Keywords: colonic polyps – colorectal neoplasms – stomach – polyps – genes – secondary prevention
Authors: Plevová Pavlína2019-08-18:An Update on Inherited Colon Cancer and Gastrointestinal Polyposis
Keywords: colonic polyps – colorectal neoplasms – stomach – polyps – genes – secondary prevention
Authors: Plevová Pavlína2019-08-18:An Update on Inherited Colon Cancer and Gastrointestinal Polyposis
Case report
Klin Onkol 2019; 32(Suppl 2): 23-27.
DOI: 10.14735/amko2019S23.
Keywords: genetic testing – hereditary cancer syndromes – DICER1 – pleuropulmonary blastoma – cystic nephroma
Authors: Hořínová Věra, Drábová Klára, Nosková Hana, Bajčiová Viera, Šoukalová Jana, Černá Leona, Hůrková Věra, Slabý Ondřej, Štěrba Jaroslav2019-08-18:DICER1 Syndrome
Keywords: genetic testing – hereditary cancer syndromes – DICER1 – pleuropulmonary blastoma – cystic nephroma
Authors: Hořínová Věra, Drábová Klára, Nosková Hana, Bajčiová Viera, Šoukalová Jana, Černá Leona, Hůrková Věra, Slabý Ondřej, Štěrba Jaroslav2019-08-18:DICER1 Syndrome
Klin Onkol 2019; 32(Suppl 2): 118-122.
DOI: 10.14735/amko2019S118.
Keywords: genes – melanoma – mesothelioma – kidney neoplasms – genetic testing
Authors: Foretová Lenka, Navrátilová Marie, Svoboda Marek, Házová Jana, Vašíčková Petra, Sťahlová Hrabincová Eva, Fabián Pavel, Schneiderová Monika, Macháčková Eva2019-08-18:BAP1 Syndrome – Predisposition to Malignant Mesothelioma, Skin and Uveal Melanoma, Renal and Other Cancers
Keywords: genes – melanoma – mesothelioma – kidney neoplasms – genetic testing
Authors: Foretová Lenka, Navrátilová Marie, Svoboda Marek, Házová Jana, Vašíčková Petra, Sťahlová Hrabincová Eva, Fabián Pavel, Schneiderová Monika, Macháčková Eva2019-08-18:BAP1 Syndrome – Predisposition to Malignant Mesothelioma, Skin and Uveal Melanoma, Renal and Other Cancers
Original articles
Klin Onkol 2019; 32(Suppl 2): 31-35.
DOI: 10.14735/amko2019S31.
Keywords: breast cancer – genes, BRCA1 – genes, BRCA2 – neoadjuvant therapy – cisplatin – carboplatin – pathologic complete response
Authors: Holánek Miloš, Bílek Ondřej, Nenutil Rudolf, Kazda Tomáš, Selingerová Iveta, Zvaríková Mária, Palácová Markéta, Vyzula Rostislav, Petráková Katarína2019-08-18:Effectiveness of Neoadjuvant Therapy with Platinum-Based Agents for Patients with BRCA1 and BRCA2 Germline Mutations – A Retrospective Analysis of Breast Cancer Patients Treated at MMCI Brno
Keywords: breast cancer – genes, BRCA1 – genes, BRCA2 – neoadjuvant therapy – cisplatin – carboplatin – pathologic complete response
Authors: Holánek Miloš, Bílek Ondřej, Nenutil Rudolf, Kazda Tomáš, Selingerová Iveta, Zvaríková Mária, Palácová Markéta, Vyzula Rostislav, Petráková Katarína2019-08-18:Effectiveness of Neoadjuvant Therapy with Platinum-Based Agents for Patients with BRCA1 and BRCA2 Germline Mutations – A Retrospective Analysis of Breast Cancer Patients Treated at MMCI Brno
Klin Onkol 2019; 32(Suppl 2): 36-50.
DOI: 10.14735/amko2019S36.
Keywords: breast cancer – CHEK2 – hereditary mutations – variants of unknown significance – functional analysis
Authors: Kleiblová Petra, Stolařová Lenka, Křížová Kateřina, Lhota Filip, Hojný Jan, Zemánková Petra, Havránek Ondřej, Vočka Michal, Černá Marta, Lhotová Klára, Borecká Marianna, Janatová Markéta, Soukupová Jana, Ševčík Jan, Zimovjanová Martina, Kotlas Jaroslav, Panczak Aleš, Veselá Kamila, Červenková Jana, Schneiderová Michaela, Burócziová Monika, Burdová Kamila, Stránecký Viktor, Foretová Lenka, Macháčková Eva, Tavandzis Spiros, Kmoch Stanislav, Macůrek Libor, Kleibl Zdeněk2019-08-18:Germline CHEK2 Gene Mutations in Hereditary Breast Cancer Predisposition – Mutation Types and their Biological and Clinical Relevance
Keywords: breast cancer – CHEK2 – hereditary mutations – variants of unknown significance – functional analysis
Authors: Kleiblová Petra, Stolařová Lenka, Křížová Kateřina, Lhota Filip, Hojný Jan, Zemánková Petra, Havránek Ondřej, Vočka Michal, Černá Marta, Lhotová Klára, Borecká Marianna, Janatová Markéta, Soukupová Jana, Ševčík Jan, Zimovjanová Martina, Kotlas Jaroslav, Panczak Aleš, Veselá Kamila, Červenková Jana, Schneiderová Michaela, Burócziová Monika, Burdová Kamila, Stránecký Viktor, Foretová Lenka, Macháčková Eva, Tavandzis Spiros, Kmoch Stanislav, Macůrek Libor, Kleibl Zdeněk2019-08-18:Germline CHEK2 Gene Mutations in Hereditary Breast Cancer Predisposition – Mutation Types and their Biological and Clinical Relevance
Klin Onkol 2019; 32(Suppl 2): 51-71.
DOI: 10.14735/amko2019S51.
Keywords: breast cancer – ovarian cancer – BRCA1 gene – BRCA2 gene – germline mutation
Authors: Macháčková Eva, Claes Kathleen, Miková Miroslava, Házová Jana, Sťahlová Hrabincová Eva, Vašíčková Petra, Trbušek Martin, Navrátilová Marie, Svoboda Marek, Foretová Lenka2019-08-18:Twenty Years of BRCA1 and BRCA2 Molecular Analysis at MMCI – Current Developments for the Classification of Variants
Keywords: breast cancer – ovarian cancer – BRCA1 gene – BRCA2 gene – germline mutation
Authors: Macháčková Eva, Claes Kathleen, Miková Miroslava, Házová Jana, Sťahlová Hrabincová Eva, Vašíčková Petra, Trbušek Martin, Navrátilová Marie, Svoboda Marek, Foretová Lenka2019-08-18:Twenty Years of BRCA1 and BRCA2 Molecular Analysis at MMCI – Current Developments for the Classification of Variants
Klin Onkol 2019; 32(Suppl 2): 72-78.
DOI: 10.14735/amko2019S72.
Keywords: ovarian neoplasms – cancer genes – mutation – massively-parallel sequencing – next generation sequencing – gene panel
Authors: Soukupová Jana, Lhotová Klára, Zemánková Petra, Vočka Michal, Janatová Markéta, Stolařová Lenka, Borecká Marianna, Kleiblová Petra, Macháčková Eva, Foretová Lenka, Koudová Monika, Lhota Filip, Tavandzis Spiros, Zikán Michal, Stránecký Viktor, Veselá Kamila, Panczak Aleš, Kotlas Jaroslav, Kleibl Zdeněk2019-08-18:Contribution of Massive Parallel Sequencing to Diagnosis of Hereditary Ovarian Cancer in the Czech Republic
Keywords: ovarian neoplasms – cancer genes – mutation – massively-parallel sequencing – next generation sequencing – gene panel
Authors: Soukupová Jana, Lhotová Klára, Zemánková Petra, Vočka Michal, Janatová Markéta, Stolařová Lenka, Borecká Marianna, Kleiblová Petra, Macháčková Eva, Foretová Lenka, Koudová Monika, Lhota Filip, Tavandzis Spiros, Zikán Michal, Stránecký Viktor, Veselá Kamila, Panczak Aleš, Kotlas Jaroslav, Kleibl Zdeněk2019-08-18:Contribution of Massive Parallel Sequencing to Diagnosis of Hereditary Ovarian Cancer in the Czech Republic
Klin Onkol 2019; 32(Suppl 2): 109-117.
DOI: 10.14735/amko2019S109.
Keywords: polyposis – gastric – hereditary – gastric cancer – gastrectomy
Authors: Foretová Lenka, Navrátilová Marie, Svoboda Marek, Grell Peter, Němec Libor, Sirotek Lukáš, Obermannová Radka, Novotný Ivo, Šachlová Milana, Fabián Pavel, Kroupa Radek, Vašíčková Petra, Házová Jana, Sťahlová Hrabincová Eva, Macháčková Eva2019-08-18:GAPPS – Gastric Adenocarcinoma and Proximal Polyposis of the Stomach Syndrome in 8 Families Tested at Masaryk Memorial Cancer Institute – Prevention and Prophylactic Gastrectomies
Keywords: polyposis – gastric – hereditary – gastric cancer – gastrectomy
Authors: Foretová Lenka, Navrátilová Marie, Svoboda Marek, Grell Peter, Němec Libor, Sirotek Lukáš, Obermannová Radka, Novotný Ivo, Šachlová Milana, Fabián Pavel, Kroupa Radek, Vašíčková Petra, Házová Jana, Sťahlová Hrabincová Eva, Macháčková Eva2019-08-18:GAPPS – Gastric Adenocarcinoma and Proximal Polyposis of the Stomach Syndrome in 8 Families Tested at Masaryk Memorial Cancer Institute – Prevention and Prophylactic Gastrectomies
