2011 47th ASCO Annual Meeting - účast ČR

Breast Cancer - HER2/ER - HER2+

Evaluation of HER2 gene status by qPCR in breast cancer samples with nonconclusive FISH.

Autoři: Mgr. Jitka Berkovcová, Ph.D.; RNDr. Radek Trojanec, Ph.D.; Mgr. Lenka Radová, Ph.D.; prof. MUDr. Zdeněk Kolář, CSc.; prof. MUDr. Bohuslav Melichar, Ph.D.; doc. MUDr. Marián Hajdúch, Ph.D.
Číslo abstraktu: 612
Kategorie: Zhoubné nádory prsu

Changes in HER2 status after neoadjuvant treatment of breast cancer.

Autoři: MUDr. Helena Skálová; Prof. MUDr. Pavel Dundr, Ph.D.; Prof. MUDr. Ctibor Povýšil, DrSc.; MUDr. Olga Přibylová, PhD.; prof. MUDr. Luboš Petruželka, CSc.; Daniel Tvrdík
Číslo abstraktu: e11110
Kategorie: Zhoubné nádory prsu

Trastuzumab plus capecitabine with or without pertuzumab in patients with HER2-positive MBC whose disease has progressed during or following trastuzumab-based therapy for first-line metastatic disease: A multicenter, randomized, two-arm, phase II stu

Autoři: M. Munoz-Mateu; A. Urruticoechea; R. Separovic; J. Erfán; Thomas Denis Bachelot; J. Canon; N. Kovalenko; E. Staroslawska; Dr. Béla Pikó; C. Veyret; MUDr. Olga Přibylová, PhD.; D.L. Ciule; J. Ratnayake; S. Das; K. Mayne; Graham Ross
Číslo abstraktu: TPS118
Kategorie: Zhoubné nádory prsu

Genitourinary Cancer - Kidney Cancer

BEVLiN: Prospective study of the safety and efficacy of first-line bevacizumab (BEV) plus low-dose interferon-α2a (IFN) in patients (pts) with metastatic renal cell carcinoma (mRCC).

Autoři: prof. MUDr. Bohuslav Melichar, Ph.D.; Sergio Bracarda; Vsevolod Matveev; I. Rusakov; Prof.MD Andrey Kaprin; A. Zyryanov; Dr. R. Janciauskiene; E. Fernebro; Prof. Gerald H. Mickisch; Prof. Martin E. Gore; A. Schulze; S. Jethwa; V. Sneller; P. Mulders; MD Joaquim Bellmunt
Číslo abstraktu: 4546
Kategorie: Genitourinární nádory

Gynecologic Cancer - Ovarian Cancer

Randomized double-blind placebo-controlled international trial of abago-vomab maintenance therapy in patients with advanced ovarian cancer after complete response to first-line chemotherapy: The Monoclonal Antibody Immunotherapy for Malignancies of t

Autoři: J. Pfisterer; J. S. Berek; A. Casado; MUDr. Karel Cwiertka, Ph.D.; Tamas Pinter; A. Pluzanska; M.D. Eric Pujade-Lauraine, Ph.D.; G. Scambia; J. B. Vermorken; Cecilia Simonelli; M Bertolotti; Angela Capriati; P. Sabbatini
Číslo abstraktu: LBA5002
Kategorie: Zhoubné gynekologické nádory

Gynecologic Cancer - Uterine Cancer

A randomized phase II (RP2) trial of ridaforolimus (R) compared with progestin (P) or chemotheraphy (C) in female adult patients with advanced endometrial carcinoma.

Autoři: A M Oza; M.D. Andres Poveda; A R Clamp; S Pignata; G. Scambia; J.M. Del Campo; M McCormack; MUDr. Libor Ševčík, Ph.D.; B M Schwartz; S Guan; R. Lee; J D Cheng; F G Haluska
Číslo abstraktu: 5009
Kategorie: Zhoubné gynekologické nádory

Leukemia, Myelodysplasia, and Transplantation - Leukemia

Results from a randomized phase III trial of decitabine versus supportive care or low-dose cytarabine for the treatment of older patients with newly diagnosed AML.

Autoři: X-G Thomas; Anna Dmoszynska; A Wierzbowska; Prof. M.D. Kazimierz Kuliczkowski, PhD; prof. MUDr. Jiří Mayer, CSc.; T Shelekhova; J Gau; Wen-Chien Chou; MD Rena Buckstein; prof. MUDr. Jaroslav Čermák, CSc.; C Kuo; O Rocafiguera; MUDr. Vladimír Koza (1954 - 2012); MD Farhad Ravandi Ravandi; M.D. Hagop M. Kantarjian
Číslo abstraktu: 6504
Kategorie: Maligní lymfomy a leukémie; Zhoubné nádory prsu

Lung Cancer - Local-Regional and Adjuvant Therapy/Small Cell - Adjuvant Therapy

A randomized phase II study of carboplatin (C) and etoposide (E) with or without pan-BCL-2 antagonist obatoclax (Ob) in extensive-stage small cell lung cancer (ES-SCLC).

Autoři: C J Langer; Dr. István Albert; P Kovacs; L.J. Blakely; G Pajkos; P Petrov; A Somfay; Aleksandra Szczesna; prof. MUDr. Petr Zatloukal (1955-2012), CSc.; A Kazarnowicz; M M Moezi; M.T. Schreeder; J. Schnyder; M.S. Berger
Číslo abstraktu: 7001
Kategorie: Zhoubné nádory plic a průdušek

Lung Cancer - Metastatic/Non-small Cell - Metastatic

Results of a randomized phase IIb study estimating overall survival of pralatrexate versus erlotinib in platinum-pretreated NSCLC

Autoři: J.D. Patel; C.G. Azzoli; G. Weems; A. Koutsoukos; prof. MUDr. Petr Zatloukal (1955-2012), CSc.; K. Kelly
Číslo abstraktu: 7554
Kategorie: Zhoubné nádory plic a průdušek

The role of specific KRAS mutation types in response to treatment by EGFR inhibitors.

Autoři: MUDr. Ondřej Fiala; prof. MUDr. Miloš Pešek, CSc.; RNDr. Lucie Benešová, Ph.D.; Barbora Belšánová; RNDr. Marek Minárik, Ph.D.
Číslo abstraktu: e18006
Kategorie: Zhoubné nádory plic a průdušek

Lymphoma and Plasma Cell Disorders - Lymphoma

Incidence of second primary malignancy (SPM) in melphalan-prednisone-lenalidomide combination followed by lenalidomide maintenance (MPR-R) in newly diagnosed multiple myeloma patients (pts) age 65 or older

Autoři: MD Antonio P. Palumbo; MD Michel Delforge, PhD; MBBS John V. Catalano, FRACP FRCPA; prof. MUDr. Roman Hájek, CSc.; MD Martin (H.) Kropff; MD Maria Teresa Petrucci; Z. Yu; MD Jay M. Mei, PhD; Meletios Athanasios Dimopoulos, MD
Číslo abstraktu: 8007

Lymphoma and Plasma Cell Disorders - Multiple Myeloma

Maintenance with rituximab after autologous stem cell transplantation in relapsed patients with CD20 diffuse large B-cell lymphoma (DLBCL): CORAL final analysis.

Autoři: MD Christian Gisselbrecht; M.D. Bertram Glass, PhD; G. Laurent; Devinder S Gill, MB ChB, MRCP (UK), FRCPath (Lond); M.D. Linch; Prof. MUDr. Marek Trněný, CSc.; D. Bron; MD Ofer Shpilberg, MPH; Hans Hagberg; M. Bargetzi; Ma David; M.D. Josette Briere; M.D. Craig H Moskowitz; MD Norbert Schmitz
Číslo abstraktu: 8004
Kategorie: Maligní lymfomy a leukémie

Patient and Survivor Care - Supportive Care

Current management of chemotherapy-induced anemia with darbepoetin alfa: The APRIORI study.

Autoři: N Bittner; MUDr. Andrea Cipková; MUDr. Heidi Móciková, Ph.D.; E. Wojciechowska-Lampka; M. Balazs; Janja Ocvirk
Číslo abstraktu: e19723
Kategorie: Podpůrná onkologická léčba, výživa nemocných a ošetřovatelská péče

Pediatric Oncology - Pediatric Solid Tumors

Busulphan-melphalan as a myeloablative therapy (MAT) for high-risk neuroblastoma: Results from the HR-NBL1/SIOPEN trial.

Autoři: M.D. Ruth L Ladenstein, MBA; Ulrike Poetschger, M.Sc.; M.D. Roberto Luksch; Prof. M.D. Penelope Brock; M.D. Victoria Castel; Prof. M.D. Isaac Yaniv; M.D. Vassilios Papadakis, Ph.D.; Genevieve Laureys; MUDr. Josef Mališ; MD Walentyna Balwierz, PhD; Dr. Ruud H. Delwel, Ph.D.; Dr. Per Kogner; M.D. Henrik Schroeder, DrMsci; A Forjaz De Lacerda; M.D. Maja Beck Popovic ; MUDr. Pavel Bician; M Garami; T Trahair; Prof. M.D. Andrew DJ Pearson; Dr. Dominique Valteau Couanet
Číslo abstraktu: 2
Kategorie: Nádory dětského a adolescentního věku

The prognostic value of semi-quantitative 123 I mIBG scintigraphy at diagnosis in high-risk neuroblastoma: Validation of the SIOPEN score method.

Autoři: V Lewington; Ulrike Poetschger, M.Sc.; MD Ariane Boubaker; M.D. Zvi Bar-Sever; B Drake; A Staudenherz; M.D. Maria Rita Castellani; M.D. Bieke Lambert; K Grange; Prof. M.D. Penelope Brock; A Garaventa; Prof. M.D. Isaac Yaniv; Dr. Dominique Valteau Couanet; M.D. Victoria Castel; A Forjaz De Lacerda; MUDr. Josef Mališ; M.D. Henrik Schroeder, DrMsci; M.D. Roberto Luksch; K Beiske; M.D. Ruth L Ladenstein, MBA
Číslo abstraktu: 9511
Kategorie: Nádory dětského a adolescentního věku

Tumor Biology - Tumor/Cell Biology

Rapid isolation of imageable circulating tumor cells.

Autoři: R M Hoffman; Mgr. Katarína Kološtová, Ph.D.; Ing. Daniela Pintérová; Prof. MUDr. Vladimír Bobek, Ph.D.
Číslo abstraktu: e21011
Kategorie: Nádorová biologie/imunologie/genetika a buněčná terapie