Klin Onkol 2013; 26(Suppl): 47-48. DOI: 10.14735/amko2013S47.
Summary
Preinvasive lesions of the vagina are relatively rare, clearly defined afflictions, originating most of all in association with the high-risk human papillomavirus infection (HR-HPV). The most frequent appearance is in coincidence with preinvasive lesions of uterine cervix and in vaginal cuff after hysterectomy. Preinvasive vaginal lesions are divided into squamous lesions (vaginal intraepithelial neoplasia) and non-squamous lesions. Vaginal adenosis belongs to non-squamous vaginal preinvasive lesions and is a precursor lesion of vaginal clear-cell carcinoma. Surgical and non-surgical techniques including laser destructive methods and local administration of 5-fluorouracile are used in the treatment of preinvasive lesions of vagina.
