Klin Onkol 2009; 22(6): 288-290.
Backgrounds: Late metastases of renal cell carcinoma (RCC) are quite common. However, metastases
in the pancreas are rare. Between 2004–2008 the Department of transplantation surgery
of the institute of clinical and experimental medicine performed 87 pancreatic resections for
tumour. From this, metastasis of RCC was histologically verified in four cases. The aim of this study
was to summarize in the form of brief case reports our experience with the surgical treatment of
pancreatic metastasis of RCC. Observation: The interval from nephrectomy to the occurrence of
pancreatic metastasis was 10, 11, 15 and 16 years. All patients were examined to exclude metastatic
generalization. Surgical treatment was: one total pancreatectomy, two subtotal pancreatectomies
and one caudal resection. Two patients had solitary pancreatic metastasis, one had
two metastases and one had multiple metastatic lesions. No complications were observed in the
postoperative period. All patients are living with survival time of 7, 23, 26 and 52 months. None
of them has signs of recurrence of the primary disease. Conclusion: The follow up in patients with
a history of RCC should be lifelong. Considering the low response of RCC and its metastases to
oncological treatment, pancreatic resection is a safe method with a low rate of complications in
patients with RCC metastases limited only to the pancreas and detected in time.
