Klin Onkol 2009; 22(4): 179-182.
Backgrounds: We present the case of small‑cell lung carcinoma metastatic to the iris, the course of the disease and management options.
Case: A 69-year-old female was diagnosed with a solid, amelanotic iris mass in her left eye. Differential diagnostics and ancillary tests subsequently led to the diagnosis of disseminated small‑cell lung carcinoma. Systemic chemotherapy was indicated
after fine needle biopsy verification of metastatic lung cancer. Iris metastasis responded
well to the chemotherapy, its regression was observed and secondary open-angle glaucoma was
controlled as well. Good visual functions were preserved during the treatment.
Conclusions: Metastatic carcinoma of the iris may be the first sign of disseminated malignant disease. Small‑cell lung carcinoma iris metastasis can be treated with chemotherapy. This treatment preserved visual functions, which enhanced the patient‘s quality of life.
