Klin Onkol 2008; 21(5): 280-288.
Abstract
Malignant prostate tumors rank with its incidence among the most frequent tumors in man in Czech Republic. Adenocarcinoma of the prostate due to its unusual behavior occupy especial position among solid tumors. Large group of these tumors are at least initially sensitive to hormonal therapy. After the introduction of PSA in the diagnostic methods we can gradually see shift of the new cases of prostate cancer to the localised stage. Those are relatively curable. Movement to less localized stage diminishes the chance of recovery, but even the metastatic adenocarcinoma can be stabilised at least for some time. The aim of therapy of hormonal refractory cancer is to maintain good quality of life and in some prolongation of survival.
