Klin Onkol 2007; 20(3): 264-268.
Invasive fungal infections represent a relatively frequent and serious complication of the treatment in cancer patients. Fungal peritonitis forms a complicated subgroup of them and has been connected with a high mortality rate. We present a case report of a 12 year old boy diagnosed with abdominal NHL and proven Candida sp. peritonitis as an early onset complication of the induction chemotherapy.
The invasive mycosis has been successfully managed using a combined approach of systemic antifungal agents, surgical interventions and monoclonal antibody efungumab (Mycograb). We present our own experience with this novel drug in a pediatric patient. A wide collaboration between specialists is accented, and therapeutic options in invasive fungal infections are discussed.