Klin Onkol 2006; 19(2): 121-123.
Summary: Liver is the predominant location of distant metastases from colorectal cancer. The metastatic foci can be isolated or multiple. From the point of view of the liver resection as well as the overall treatment management, the metastatic liver diseases may be divided into the three groups: isolated, multiple, and non-resectable. The treatment of isolate liver metastases is based on resection. Due to the „bloodless“ liver resection technique it is possible to minimize the resection size, perform a non-anatomical resection as well as a laparoscopically assisted surgery. Surgery provides better results in combination with oncological treatment. Historically, resections were not indicated in patients with multiple liver metastases. Due to development in surgery, oncology, and radiology, these patients now also represent liver resection candidates, namely for the „two-stage resection“. This therapeutic procedure has improved long-term survival. In the group of patients with non-resectable liver metastases only palliative oncology and radiology treatment is recommended. Curative and non-curative liver resections are beneficial and improve survival in selected patients. Good results may be achieved only by complex multimodal treatment based on cooperation of a surgeon, an oncologist, and a
radiologist.
