Klin Onkol 2005; 18(4): 149-151.
Summary:
Purpose: The purpose of our study was to evaluate an upcoming breast cancer diagnostic modality based on measurements of the red light absorption in the breast and response on pressure stimulus inducing circulating blood volume changes.
Patients and Method: Patients (n=100) with suspicious mammography finding underwent Dynamic Optical Breast Imaging (DOBI) followed by core-cut biopsy in Masaryk Memorial Cancer Institute. Sensitivity and specificity were calculated to compare DOBI with mammography. Results: Both sensitivity and specificity (71% and 64% respectively) indicates that DOBI can be a promising minimum-stress method in malignant breast lesion detection.