Klin Onkol 2002; 15(1): 17-22.
Summary: The barrier function is the ability of the intestinal mucosa to prevent the passage of macromolecules. The damaged intestinal barrier plays possible role of pathogenesis of some diseases, after operations, or in critically ill patients, polytrauma, inflammatory bowel diseases, drug induced enteropathy, celiac disease and rheumatological diseases. Increased intestinal permeability is associated with cytostatic therapy and radioterapy. The noninvasive assessment of intestinal permeability in humans has a 27- year history. There is much controversy in the literature.
