Klin Onkol 2001; 14(Zvláštní číslo): 10-12.
Summary: Inoperable advanced stage lung cancer is usually treated by radiation therapy. For these cases palliation of symptoms becomes the main purpose of treatment. Palliative radiotherapy is indicated not only for the treatment of advanced primary tumours, but also for patients with superior vena cava syndrome, with Pancoast syndrome and with obstruction of the bronchus followed by atelectasis. Effective palliation by radiotherapy can be freguently obtained also in patients with bone metastases, brain metastases or metastases in other sites. We can use two besic fractionation schedules in palliative radiotherapy: palliative accelerated irradiation ( e.g. 5x4 Gy/d, 5x5 Gy/d, 1x8-10Gy/d) or conventionally fractionated radiotherapy (2-3 Gy/d with a total dose of 40-60 Gy). Both fractionation schedules provide a comparable palliative effect.