Klin Onkol 2000; 13(1): 27-29.
Summary: Background. We decided to confirm results of flow cytometry, histology and cytology in the detection of bone marrow infiltration in patients with non-Hodgkin’s lymphomas. Design and Subjects: In a retrospective study, we examined the correlation between flow cytometric, histological, and cytological findings in bone marrow of 59 patients treated in our department. According to the REAL classification, the distribution of all cases of NHL was as follows: 94.9 % B-cell NHLs, and 5.1 % T-cell NHLs. Results. A 71.2 % conformity of flow cytometric, histological, and cytological findings in evaluation of bone marrow infiltration was observed. A 60.9 % conformity between flow cytometric diagnosis and histological diagnosis was found. A discussion of individual types of NHLs and their histological and flow cytometric diagnostics follow. Conclusion: We recommend flow cytometric analysis of bone marrow in patients with non-Hodgkin’s lymphomas.
