Summary: During the period 1992-1997, 76 patients suffering from lung cancer and some duplicate malignant tumours were treated in both Czech and Slovak institutes. There were 51 Czech duplicate tumour patients selected from 1238 lung cancer patients and 21 Slovak from 275, an average of 4.36% of Czech and 8% of Slovak lung cancer populations (p<0.05). Three of the Czech patients suffered from triplicate malignancies. The highest incidence of multiple tumours is in 60-69 old patients in both groups. The most frequent locations of second malignancy in men were head and neck cancer, second lung cancer and gastrointestinal tumours, whereas in women the first two were uterus and breast cancers. The highest risk of second malignancy appearence is till seven years after the first one. Common risk factors were cigarette smoking, genetic predisposition, occupational exposure to carcinogens and probably previous chemotherapy and/or radiotherapy as well as combinations of those. In general, in cancer patients, there is significant risk to develop a second malignant tumour, particulary during the first seven years after the first one. Our results as well as results of other authors justify an active therapeutic strategy even in such patients. lt has been demonstrated that therapeutic outcome is comparable with other lung cancer patients.
Duplicity of malignant tumours in lung, cancer patients
