The influence of cell kinetics on the radiotherapy results in quickly and slowly proliferating tumors

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Klin Onkol 1996; 9(1): 18-20.

Summary: Cell kinetics parameters LI, Ts and Tpot were studied by incorporation of BUDR into cellular DNA and subsequent ans lysis by flow cytometry in a group of 12 patients with various tumours. The authors consider Tpot to be a very promising predictor c the rate repopulation during radiotherapy. Patients in this group were at a higher risk of treatment failure if the Tpot values were low