Summary: The strategy of individualised complex therapy for gestational trophoblastic disease must be based on an exact estimation of pretherapeutic risk factors. After analysis of the risk factors among 113 women undergoing therapy in our centre, we estimated statistical importance of individual risk factors. Current management is based on these factors. A therapeutic plan is necessary for individualization the cure. Strategy of therapy of GTD in low and medium risk groups of patients depends on the wish of another pregnancy more than in other groups. The optimal result of the therapy of GTD should not be simply die complete cure but also a preservation of me uterus and of the ovarian function. Low risk patients receive chemotherapy OM or AtD. Medium risk patients receive chemotherapy EMA - MO -1, EMA - CO -1, EMA - PE -1. In the period from 1/1991 to 6/1994, we treated 30 patients with low and medium risk with a cure rate of 100%.
Current treatment management of low and mediate risk group GTD (Gestational Trophoblastic Disense) in CZTDC Prague
