Klin Onkol 1995; 8(6): 165-167.
Summary: Research conducted over the past few decades has shown that growth of solid neoplasms is dependent on tumor vascularization. Many compounds were identified that can stimulate angiogenesis and others that inhibit it. These discoveries led therapists to search for drugs that inhibit angiogenesis. The authors summarize the current state of the art in this rapidly evolving field. Such information may result in development of new therapeutic interventions based on tumor vascularization suppression.
