The alteration of the expression of differentiated and MHC cell lines induced by the retinoid acid and 1,25 (OH), vitamin-D

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Klin Onkol 1994; 7(4): 114-116.

Cell surface alterations induced by all-trans retinoic acid in promyelocytic leukemia cell line HL-60 were typical for the induction of granulocytic differentiation, and monocyte/macrophage differentiation induced by vitamin D3 in both HL-60 and mono-biastoid U-937 cells. Retinoids induced the up-regulation of protectin (CD59 antigen) on the cell surface of human breast carcinoma line BT-20.