Klin Onkol 1991; 4(4): 117-121.
Summary: At the Department of Surgery in Plzeň one male and 122 female patients were operated on for breast cancer in the years 1977 and 1978. In five women a separate carcinoma of the other breast occured, either previously, simultaneously or subsequently. Tumor duplicity occured in five female patients. Breast tumors were accompanied by carcinoma of ovary (two cases), endometrial carcinoma (twice) and carcinoma of pancreas. Prior to operation, most females had been submitted to preoperative staging (18, 48, 46, and 2 patients in stages 1, 2, 3 and 4 respectively). Peak occurence of breast tumors was traced in patients between 65 and 70 years of age. In 114 women, the period of survival is known.
The survival-rate was 45% and 24% at 5 and 10 years after operation resp. 20% of patients are still alive 11 - 12 years after operation. Survival-rate in the most frequent type of carcinoma-ductal infiltrative carcinoma - was 42% and 21%, 5 and 10 years after operation resp. The difference is statistically significant according to Wil-coxon test.
Currently, i. e. 11 and 12 years after operation, 23 former patients are still alive. Six of these had a prognostically more auspicious type of tumor in terms of histology (papillocarcinoma, medullar, gelatinous of lobullar infiltrative carcinoma). The remaining 17 patients suffered from ductal infiltrative carcinoma, sometimes with further unfavorable prognostic parameters, e. g. 3rd clinical stage, metastases in axillary nodes at the time of operation as well as in the postoperative period, scar-situated relapses (in several cases reccurrent), or isolated hematogenous metastases. In two of these patients, carcinoma of the other breast occured.
The preoperative clinical evaluation of the axillary nodes for metastatic disease in comparison with the histological findings was incorrect - either falsely positive or falsely negative - in 22 percent of the cases.
